Three Straight Quarters of Institutional Retreat Leave SDGR’s Float Treading Water

Insider selling and a rising put/call ratio signal growing caution amid the pullback

SDGR Schrödinger, Inc.

In this report

01

Institutional Ownership

Quarterly ownership trends, direction, investor count

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02

Position Flow Analysis

Flow ratio, conviction, new vs closed positions

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03

Float & Options Context

Put/call ratio, free float estimate, hedging activity

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04

Insider Trading Patterns

Insider buys/sells, top transactions, cluster buying, post-buy returns

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05

Smart Money Summary

Convergence/divergence flags, key takeaways

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Institutional Ownership Trends

Schrödinger, Inc. (SDGR) — Ownership Profile

Institutional ownership of Schrödinger, Inc. (SDGR) has slipped to 89.65% as of 2026Q1, reflecting a modest decline of 0.79 percentage points from the prior quarter. The negative change marks three consecutive quarters of decreasing institutional stakes, satisfying the threshold for sustained distribution, while still keeping ownership just below the heavily institutionalized 90% benchmark. The investor base comprises 237 institutions, indicating a relatively broad but slightly contracting pool of holders.

Ownership Overview

SDGR

The current institutional positioning suggests a gradual pullback by large investors, as evidenced by the sustained distribution trend over three quarters. Although ownership remains high at 89.65%, the slight decline and modest reduction in investor count could signal tightening float and reduced liquidity pressure. Monitoring whether this distribution persists or reverses will be key to gauging future institutional sentiment.

Position Flow Analysis

Schrödinger, Inc. (SDGR) — Position Flows

Schrödinger, Inc. (SDGR) exhibits a strong net accumulation signal, reflected by a current flow ratio of 1.68, well above the 1.5 threshold that denotes robust buying pressure from investors entering or expanding positions. The conviction ratio of 0.69 indicates that existing shareholders are also adding to their stakes, reinforcing the positive sentiment. With a latest net flow of 71 (net inflow units), both new capital and increased commitment from current holders suggest a bullish positioning trend over the recent period.

Position Flow Metrics

SDGR

The flow ratio of 1.68 signals that institutions are actively opening fresh positions, while the conviction ratio of 0.69 confirms they are concurrently increasing allocations to existing holdings. This convergence of new inflows and heightened conviction underscores a strong accumulation phase, implying confidence in the company's near‑term outlook.

Float & Options Context

Schrödinger, Inc. (SDGR) — Float & Options

Schrödinger, Inc. (SDGR) exhibits a constrained free‑float of approximately 10.35%, derived from its high institutional ownership of 89.65%. A put/call ratio of 1.25 that has been rising for three consecutive quarters signals increasing bearish hedging pressure among options traders, suggesting that market participants are seeking protection against downside risk despite the limited supply of tradable shares.

Float & Options Overview

SDGR

The combination of a high put/call ratio (>1.0) and a rising trend points to growing defensive positioning, which may reflect concerns about near‑term price volatility or earnings uncertainty. Meanwhile, the constrained float (<15%) limits liquidity and can amplify price moves, creating both squeeze potential on positive news and heightened downside risk if selling pressure intensifies.

Float & Options Context

Schrödinger, Inc. (SDGR) — Put/Call Ratio

Insider Trading Patterns

Schrödinger, Inc. (SDGR) — Insider Activity

Over the past twelve months, Schrödinger, Inc. (SDGR) recorded no insider purchases and 16 insider sales totaling $1,295,912, yielding a buy/sell value ratio of 0.0, well below the 0.2 threshold that flags heavy selling. The most material transactions were two consecutive sales by President & CEO Farid Ramy on April 16‑17, 2026, each disposing of 43,000 shares for roughly $527k, and a sale by the President of R&D, Therapeutics on April 14, 2025 amounting to 8,378 shares worth $210k; these sales represent over 80% of the total insider sell volume.

Insider Activity Summary

SDGR

The absence of insider buying combined with concentrated selling by the CEO suggests a bearish signal, especially given that the sales exceed typical compensation‑related disposals in size and timing. No clustering of purchases was observed, and historical post‑buy success rates are irrelevant here due to zero buy activity, leaving the insider sentiment largely negative for the near term.

Insider Trading Patterns

Schrödinger, Inc. (SDGR) — Insider Timeline

Smart Money Summary

Schrödinger, Inc. (SDGR) — Summary & Implications

Institutional ownership of Schrödinger, Inc. stands at an elevated 89.65%, reflecting a highly concentrated shareholder base that has modestly declined by 0.79 percentage points over the last quarter. The flow classification of “strong accumulation” indicates net buying pressure from institutions, yet the concurrent insider selling—recorded as a neutral 0.0 B/S ratio—suggests insiders are offloading shares at a rate comparable to their purchases. Adding nuance, the put/call ratio has risen to 1.25, surpassing the 1.5 threshold for heightened bearish sentiment, and aligns with the observed institutional distribution, pointing to mixed signals among smart money participants.

Smart Money Dashboard

Key Takeaways

Institutional ownership is very high at 89.65%, limiting further inflow potential but indicating strong existing confidence.
Institutions have been net buyers (strong accumulation) despite a slight quarterly decline in ownership percentage.
Insider activity shows neutral selling pressure, which may be routine and not necessarily negative for the business.
The put/call ratio of 1.25 signals increasing bearish options positioning, diverging from institutional buying sentiment.
Overall smart money positioning is mixed: institutional accumulation suggests confidence, while insider sales and rising put/call ratios introduce a cautious tone.

SDGR

The dominant institutional ownership coupled with a strong accumulation flow class underscores confidence from large investors, but the recent insider sell‑off and elevated put/call ratio introduce caution. The divergence between institutional buying and insider selling may reflect routine compensation sales rather than fundamental concerns, while the rising bearish options activity could signal short‑term downside pressure.

SDGR

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Report written 2026-06-07 • Finexus

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